He started acting in 1955 when he was only 15 years old. When director Mario Barri thought of doing a sequel to ‘Palaris,’ a movie produced and starred by Fernando Poe, he got the son for the title role, "Anak ni Palaris," and opted for the monicker Fernando Poe, Jr. as the new actor’s screen name.The movie, with Rosita Noble as Poe’s leading lady, was released in January 1955.
Lo' Waist Gang (1956) - Poe's First Taste of Fame and Stardom
Reached fame and stardom via Larry Santiago Productions of "Lo' Waist Gang," released in July 1956. The movie was such a big hit that it started a fashion fad: low waist pants.
Kamay ni Cain (1957) - His First Nominated Film for Best Supporting Actor.
He played villain to lead actor, Zaldy Zshornack. His first with Director Gerardo (Gerry) de Leon.
Markado (1960) -Established him as the country's Top Action and Box-office star.
It was in the movie, "Markado," produced by a new outfit, Hollywood- Far East Productions, released in 1960, that marked and established him as a major action star, where he demanded a huge talent fee for his services. He quoted his talent fee at P8,000, a very huge sum that time.
Established FPJ Productions in 1962 with its initial offering, "Batang Maynila."